Integratie van microfluïdische monstervoorbereiding met PCR-detectie om de effecten

mapi-research

Integratie van microfluïdische monstervoorbereiding met PCR-detectie om de effecten

Klinisch nut van Droplet Digital PCR om BCR-ABL1-transcripten van patiënten met Philadelphia-chromosoom-positieve aigu lymfoblastische leukemie te monitoren Put up-chimere antigeenreceptor 19/22 T-celcocktailtherapie

La leucémie aiguë lymphoblastique à chromosome Philadelphie (  LAL Ph + ) représente 20 à 30 % des sufferers adultes atteints de LAL, caractérisée par une translocation de   (9, 22) . Les inhibiteurs de la tyrosine kinase (ITK) ont considérablement amélioré les résultats, même s’il existe encore des problèmes, notamment des rechutes dues à des mutations résistantes aux médicaments et à une profondeur de rémission moléculaire sous-optimale. Auparavant, nous avons signalé l’innocuité et l’efficacité de la perfusion séquentielle de l’ immunothérapie des cellules T du récepteur de l’antigène chimérique CD19/22 (CAR-T) dans le traitement des néoplasmes à cellules B en rechute/réfractaires (R/R), y compris les cas avec Ph + TOUT. Compte tenu de la possibilité d’une réaction plus profonde, on s’attendait à ce que davantage de sufferers atteignent une réponse optimale de maladie résiduelle minimale (MRD). Une méthode different, la PCR numérique à gouttelettes duplex (ddPCR) à haute sensibilité a été établie, qui pourrait fournir une quantification absolue de la MRD sans avoir besoin de courbes d’étalonnage. Ici, nous avons collecté rétrospectivement 95 échantillons de moelle osseuse de 10 sufferers atteints de R/R Ph + , qui ont reçu 19/22 CAR-T-cell thérapie cocktail.

Notamment, la rémission moléculaire séquentielle pendant plus de three mois (SMR3), un indicateur significatif basé sur la ddPCR après la perfusion de CAR-T a été établie, qui a été définie comme une rémission moléculaire séquentielle pendant pas moins de three mois avec une MRD négative. Dans cette cohorte, aucune récidive n’a été observée chez six sufferers ayant obtenu une SMR3, dont quatre ont accepté une allogreffe de cellules souches hématopoïétiques (allo-HSCT) après un régime de cellules CAR-T. Malheureusement, les quatre autres sufferers qui n’ont pas atteint le SMR3 ont rechuté et n’ont pas reçu de traitement spécifique supplémentaire à l’ exception du régime CAR-T.. En résumé, la ddPCR peut être une different, surtout lorsque l’acide nucléique était insuffisant en pratique clinique. L’absence de SMR3 peut être un avertissement précoce d’une rechute potentielle après CAR-T et indiquer l’initiation d’autres thérapies, y compris l’allo-HSCT.

Kwantitatieve detectie et monitoring van  Colletotrichum siamense  in rubberbomen rencontré behulp van PCR en temps réel

Colletotrichum siamense  est l’un des brokers pathogènes les plus importants de l’hévéa en Asie. La détection et la quantification adéquates des  populations de  C. siamense dans les hévéas sont importantes pour le suivi des épidémies de la maladie. Dans cette étude, nous avons développé une méthode de PCR en temps réel basée sur l’ITS pour détecter efficacement l’   hévéa infectant C. siamense , qui a détecté de manière fiable aussi peu que 100 fg d’ADN génomique, 100 copies d’ADN cible et 20 conidies. Le protocole PCR en temps réel a reconnu tous les   isolats de C. siamense collectés dans trois provinces de Chine , tandis qu’aucune amplification n’a été observée avec l’hévéa et ses autres brokers pathogènes. Détection et quantification de  C. siamense ont été réalisées sur des feuilles de caoutchouc infectées artificiellement et naturellement.

Nous pouvions encore détecter  C. siamense  dans des mélanges de plantes dont seulement 0,0001 % des tissus étaient infectés. Une accumulation d’  ADN de  C. siamense a été observée pendant tout le processus d’an infection aux trois stades phénologiques des feuilles, suggérant que la méthode PCR en temps réel peut être utilisée pour surveiller le   développement de C. siamense dans les arbres à caoutchouc. Enfin, la méthode a permis la détection de  C. siamense  dans des feuilles d’hévéas naturellement infectées et asymptomatiques dans les champs. Par rapport aux méthodes de détection antérieures, la méthode PCR en temps réel est plus spécifique et plus wise, et sera d’une grande utilité pour les études visant à mieux comprendre l’épidémiologie de la maladie foliaire à Colletotrichum, ainsi que la prédiction du risque de maladie et la proposition de contrôle.

Integratie van microfluïdische monstervoorbereiding met PCR-detectie om de effecten van gelijktijdige scheiding van DNA-remmers en uitwisseling van DNA-oplossingen te onderzoeken

Dans cet article, nous avons appliqué un dispositif microfluidique à canal incurvé pour séparer l’ADN de l’eau contenant des inhibiteurs de PCR et les laver simultanément dans de l’eau propre pour la détection à l’aide d’un thermocycleur PCR transportable. L’ échantillonnage de l’ADN environnemental (eDNA) est devenu une approche d’enquête efficace pour détecter les organismes rares. Cependant, les molécules d’ADNe à faible focus peuvent être masquées par des inhibiteurs de PCR lors de l’amplification et de la détection, ce qui augmente le risque de fake négatifs. Par conséquent, des applied sciences pour la séparation et le lavage de l’ADN sur website sont nécessaires de toute urgence. Notre dispositif consistait en un microcanal en demi-cercle avec une entrée d’échantillon d’inhibiteur d’ADN , une entrée de tampon propre et plusieurs sorties.

En utilisant les forces d’inertie induites par le flux, des microparticules conjuguées à l’ADN de 10 m ont été concentrées sur la paroi interne du microcanal incurvé tandis que la séparation des microparticules conjuguées à l’inhibiteur de 1 m et le lavage de l’ADN ont été réalisés simultanément avec le flux de Dean. Nous avons réalisé une focalisation, une isolation et un lavage singleplex de particules de 10 μm avec une efficacité de 94,5 ± 2,0 % . Dans des expériences en duplex avec des particules de 1 m et 10 m, des particules plus grosses ont été lavées avec une efficacité de 92,1 ± 1,6 % et une pureté de 79 ± 2 %.

En fonctionnalisant en floor les microparticules avec des groupes d’affinité contre l’ADN de saumon atlantique et l’acide humique (HA), et en traitant des échantillons de différentes concentrations dans notre appareil, nous avons réalisé une purification et une détection efficaces des molécules d’ADN à l’aide du thermocycleur PCR transportable. Notre méthode a significativement diminué les cycles de quantification PCR de Cq > 38 à Cq = 30,35 ± 0,5, ce qui a confirmé l’amélioration de l’amplification PCR. Le dispositif proposé fait un pas en avant prometteur dans la préparation d’échantillons vers un dispositif intégré qui peut être utilisé pour la purification et l’échange simultanés de resolution d’ADN dans des purposes de surveillance environnementale au level de besoin.

mapi-research
mapi-research

 

GPR119 Antibody

1-CSB-PA007283
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GPR119. Recognizes GPR119 from Human. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/10000

GPR119 Antibody

DF4892 200ul
EUR 304
Description: GPR119 Antibody detects endogenous levels of total GPR119.

GPR119 Antibody

ABD4892 100 ug
EUR 438

GPR119 antibody

70R-31399 100 ug
EUR 327
Description: Rabbit polyclonal GPR119 antibody

Gpr119/ Rat Gpr119 ELISA Kit

ELI-08203r 96 Tests
EUR 886

GPR119 Polyclonal Antibody

ES4819-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against GPR119 from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

GPR119 Polyclonal Antibody

ES4819-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against GPR119 from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

GPR119 Polyclonal Antibody

ABP53820-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of GPR119 from Human. This GPR119 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human GPR119 at AA rangle: 160-240

GPR119 Polyclonal Antibody

ABP53820-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of GPR119 from Human. This GPR119 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human GPR119 at AA rangle: 160-240

GPR119 Polyclonal Antibody

ABP53820-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of GPR119 from Human. This GPR119 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human GPR119 at AA rangle: 160-240

GPR119 Polyclonal Antibody

40973-100ul 100ul
EUR 252

GPR119 Polyclonal Antibody

40973-50ul 50ul
EUR 187

GPR119 siRNA

20-abx918416
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

GPR119 siRNA

20-abx918417
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

GPR119 siRNA

20-abx902267
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

GPR119 Peptide

45-692P 0.1 mg
EUR 338
Description: GPR119 Peptide

GPR119 Polyclonal Conjugated Antibody

C40973 100ul
EUR 397

GPR119 cloning plasmid

CSB-CL840575HU-10ug 10ug
EUR 233
Description: A cloning plasmid for the GPR119 gene.

GPR119 Rabbit pAb

A18544-100ul 100 ul
EUR 308

GPR119 Rabbit pAb

A18544-200ul 200 ul
EUR 459

GPR119 Rabbit pAb

A18544-20ul 20 ul
EUR 183

GPR119 Rabbit pAb

A18544-50ul 50 ul
EUR 223

GPR119 Blocking Peptide

20-abx162463
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

GPR119 Blocking Peptide

DF4892-BP 1mg
EUR 195

Polyclonal GPR119 Antibody (aa186-235)

APR16477G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GPR119 (aa186-235). This antibody is tested and proven to work in the following applications:

Polyclonal GPR119 Antibody (Cytoplasmic Domain)

APR16478G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GPR119 (Cytoplasmic Domain). This antibody is tested and proven to work in the following applications:

Polyclonal GPR119 Antibody (Cytoplasmic Domain)

APR16479G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GPR119 (Cytoplasmic Domain). This antibody is tested and proven to work in the following applications:

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Human GPR119 shRNA Plasmid

20-abx965265
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Rat GPR119 shRNA Plasmid

20-abx989158
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Mouse GPR119 shRNA Plasmid

20-abx982252
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Human GPR119 ELISA KIT

ELI-48829h 96 Tests
EUR 824

Mouse Gpr119 ELISA KIT

ELI-09750m 96 Tests
EUR 865

GPR119 Recombinant Protein (Rat)

RP203282 100 ug Ask for price

GPR119 Recombinant Protein (Human)

RP039541 100 ug Ask for price

GPR119 Recombinant Protein (Mouse)

RP139418 100 ug Ask for price

G-Protein Coupled Receptor 119 (GPR119) Antibody

20-abx121407
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

G-Protein Coupled Receptor 119 (GPR119) Antibody

abx432763-200ul 200 ul
EUR 384

G-Protein Coupled Receptor 119 (GPR119) Antibody

abx215630-100ug 100 ug
EUR 439

G Protein-Coupled Receptor 119 (GPR119) Antibody

20-abx324143
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Gpr119 ORF Vector (Rat) (pORF)

ORF067762 1.0 ug DNA
EUR 506

Gpr119 ORF Vector (Mouse) (pORF)

ORF046474 1.0 ug DNA
EUR 506

GPR119 ORF Vector (Human) (pORF)

ORF013181 1.0 ug DNA
EUR 354

GPR119 sgRNA CRISPR Lentivector set (Human)

K0895801 3 x 1.0 ug
EUR 339

Gpr119 sgRNA CRISPR Lentivector set (Rat)

K7204201 3 x 1.0 ug
EUR 339

Gpr119 sgRNA CRISPR Lentivector set (Mouse)

K3605701 3 x 1.0 ug
EUR 339

GPR119 sgRNA CRISPR Lentivector (Human) (Target 1)

K0895802 1.0 ug DNA
EUR 154

GPR119 sgRNA CRISPR Lentivector (Human) (Target 2)

K0895803 1.0 ug DNA
EUR 154

GPR119 sgRNA CRISPR Lentivector (Human) (Target 3)

K0895804 1.0 ug DNA
EUR 154

Gpr119 sgRNA CRISPR Lentivector (Rat) (Target 1)

K7204202 1.0 ug DNA
EUR 154

Gpr119 sgRNA CRISPR Lentivector (Rat) (Target 2)

K7204203 1.0 ug DNA
EUR 154

Gpr119 sgRNA CRISPR Lentivector (Rat) (Target 3)

K7204204 1.0 ug DNA
EUR 154

GPR119 3'UTR GFP Stable Cell Line

TU059210 1.0 ml
EUR 2333

Gpr119 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3605702 1.0 ug DNA
EUR 154

Gpr119 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3605703 1.0 ug DNA
EUR 154

Gpr119 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3605704 1.0 ug DNA
EUR 154

GPR119 Protein Vector (Human) (pPB-C-His)

PV052721 500 ng
EUR 481

GPR119 Protein Vector (Human) (pPB-N-His)

PV052722 500 ng
EUR 481

GPR119 Protein Vector (Human) (pPM-C-HA)

PV052723 500 ng
EUR 481

GPR119 Protein Vector (Human) (pPM-C-His)

PV052724 500 ng
EUR 481

GPR119 Protein Vector (Rat) (pPB-C-His)

PV271046 500 ng
EUR 603

GPR119 Protein Vector (Rat) (pPB-N-His)

PV271047 500 ng
EUR 603

GPR119 Protein Vector (Rat) (pPM-C-HA)

PV271048 500 ng
EUR 603

GPR119 Protein Vector (Rat) (pPM-C-His)

PV271049 500 ng
EUR 603

GPR119 Protein Vector (Mouse) (pPB-C-His)

PV185894 500 ng
EUR 603

GPR119 Protein Vector (Mouse) (pPB-N-His)

PV185895 500 ng
EUR 603

GPR119 Protein Vector (Mouse) (pPM-C-HA)

PV185896 500 ng
EUR 603

GPR119 Protein Vector (Mouse) (pPM-C-His)

PV185897 500 ng
EUR 603

GPR119 3'UTR Luciferase Stable Cell Line

TU009210 1.0 ml
EUR 2333

Gpr119 3'UTR GFP Stable Cell Line

TU255325 1.0 ml Ask for price

Gpr119 3'UTR Luciferase Stable Cell Line

TU205325 1.0 ml Ask for price

Gpr119 3'UTR GFP Stable Cell Line

TU158968 1.0 ml Ask for price

Gpr119 3'UTR Luciferase Stable Cell Line

TU108968 1.0 ml Ask for price

GPR119 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV629167 1.0 ug DNA
EUR 682

GPR119 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV629171 1.0 ug DNA
EUR 682

GPR119 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV629172 1.0 ug DNA
EUR 682

GPR119 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0895805 3 x 1.0 ug
EUR 376

Gpr119 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K7204205 3 x 1.0 ug
EUR 376

Gpr119 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3605705 3 x 1.0 ug
EUR 376

GPR119 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0895806 1.0 ug DNA
EUR 167

GPR119 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0895807 1.0 ug DNA
EUR 167

GPR119 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0895808 1.0 ug DNA
EUR 167

GPR119 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV629168 1.0 ug DNA
EUR 682

GPR119 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV629169 1.0 ug DNA
EUR 740

GPR119 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV629170 1.0 ug DNA
EUR 740

Gpr119 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K7204206 1.0 ug DNA
EUR 167

Gpr119 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K7204207 1.0 ug DNA
EUR 167

Gpr119 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K7204208 1.0 ug DNA
EUR 167

Gpr119 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3605706 1.0 ug DNA
EUR 167

Gpr119 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3605707 1.0 ug DNA
EUR 167

Gpr119 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3605708 1.0 ug DNA
EUR 167

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 277

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 277

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 277

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 277

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 277

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 277

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 277

Anti-Anti-DDB1 Antibody

A00333 100uL
EUR 455
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu
  • EUR 5698.00
  • EUR 3011.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 1 plate of 96 wells
EUR 432
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-FGF1 Antibody

RP1005 100ug/vial
EUR 334

Anti-FGF2 Antibody

RP1006 100ug/vial
EUR 334

Anti-IL3 Antibody

RP1008 100ug/vial
EUR 334

Anti-IL4 Antibody

RP1009 100ug/vial
EUR 334

Anti-DDT Antibody

RP1011 100ug/vial
EUR 334

Anti-IL6 Antibody

RP1012 100ug/vial
EUR 294

Anti-IL7 Antibody

RP1013 100ug/vial
EUR 294

Anti-IL10 Antibody

RP1014 100ug/vial
EUR 334

Anti-IL10 Antibody

RP1015 100ug/vial
EUR 294

Anti-IL10 Antibody

RP1016 100ug/vial
EUR 334

Anti-IL18 Antibody

RP1017 100ug/vial
EUR 334

Anti-CEACAM5 Antibody

RP1018 100ug/vial
EUR 334

Anti-MIF Antibody

RP1020 100ug/vial
EUR 294

Anti-NGF Antibody

RP1025 100ug/vial
EUR 294

Anti-FOXP3 Antibody

RP1032 100ug/vial
EUR 334

Anti-MUC2 Antibody

RP1038 100ug/vial
EUR 334

Anti-ATM Antibody

RP1040 100ug/vial
EUR 294

Anti-CBS Antibody

RP1041 100ug/vial
EUR 334

Anti-IL3 Antibody

RP1046 100ug/vial
EUR 294

Anti-IL13 Antibody

RP1047 100ug/vial
EUR 294

Anti-IL13 Antibody

RP1048 100ug/vial
EUR 294

Anti-MBD2 Antibody

RP1049 100ug/vial
EUR 294

Anti-FRZB Antibody

RP1061 100ug/vial
EUR 294

Anti-HGF Antibody

RP1062 100ug/vial
EUR 294

Anti-PLD1 Antibody

RP1063 100ug/vial
EUR 294

Anti-MAFA Antibody

RP1066 100ug/vial
EUR 294

Anti-SFRP4 Antibody

RP1067 100ug/vial
EUR 294

Anti-AGFG1 Antibody

RP1071 100ug/vial
EUR 294

Anti-SP1 Antibody

RP1072 100ug/vial
EUR 294

Anti-TLR8 Antibody

RP1073 100ug/vial
EUR 294

Anti-CD59 Antibody

RP1076 100ug/vial
EUR 334

Anti-TSG101 Antibody

RP1078 100ug/vial
EUR 294

Anti-CYP7A1 Antibody

RP1079 100ug/vial
EUR 294

Anti-DMRT1 Antibody

RP1083 100ug/vial
EUR 334

Anti-FABP4 Antibody

RP1085 100ug/vial
EUR 334

Anti-PTOV1 Antibody

RP1087 100ug/vial
EUR 294

Anti-Wnt7a Antibody

RP1088 100ug/vial
EUR 334

Anti-MMP12 Antibody

RP1089 100ug/vial
EUR 294

Anti-HSD11B2 Antibody

RP1094 100ug/vial
EUR 294

Anti-CD33 Antibody

RP1105 100ug/vial
EUR 334

Anti-VIP Antibody

RP1108 100ug/vial
EUR 334

Anti-SHANK3 Antibody

RP1109 100ug/vial
EUR 294

Anti-ADH5 Antibody

RP1111 100ug/vial
EUR 334

Anti-Calbindin Antibody

M03047-2 100ul
EUR 397
Description: Chicken Polyclonal Calbindin Antibody. Validated in IF, IHC, WB and tested in Bovine, Human, Mouse, Rat.

Anti-Fibrillarin Antibody

M03178-4 100ul
EUR 397
Description: Rabbit Polyclonal Fibrillarin Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat.

Anti-Fibrillarin Antibody

M03178-5 100ul
EUR 397
Description: Chicken Polyclonal Fibrillarin Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-Parvalbumin Antibody

M04041-2 100ul
EUR 397
Description: Chicken Polyclonal Parvalbumin Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Calretinin Antibody

M04255-3 100ul
EUR 397
Description: Rabbit Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Calretinin Antibody

M04255-4 100ul
EUR 397
Description: Chicken Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat.

Anti-Laminin Antibody

M04965 100ul
EUR 397
Description: Rabbit Polyclonal Laminin Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-Secretagogin Antibody

M10629-1 100ul
EUR 397
Description: Rabbit Polyclonal Secretagogin Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Secretagogin Antibody

M10629-2 100ul
EUR 397
Description: Chicken Polyclonal Secretagogin Antibody. Validated in IF, IHC, WB and tested in Bovine, Human, Mouse, Rat.

Anti-MeCP2 Antibody

M00047-1 100ul
EUR 397
Description: Rabbit Polyclonal MeCP2 Antibody. Validated in IHC, WB and tested in Human, Monkey, Mouse, Rat.

Anti-GAPDH Antibody

M00227-4 100ul
EUR 397
Description: Rabbit Polyclonal GAPDH Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-Vimentin Antibody

M00235-4 100ul
EUR 397
Description: Rabbit Polyclonal Vimentin Antibody. Validated in IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat.

Anti-Vimentin Antibody

M00235-5 100ul
EUR 397
Description: Chicken Polyclonal Vimentin Antibody. Validated in IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-CNP Antibody

M01017-2 100ul
EUR 397
Description: Rabbit Polyclonal CNP Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-CNP Antibody

M01017-3 100ul
EUR 397
Description: Chicken Polyclonal CNP Antibody. Validated in IHC, WB and tested in Equine, Pig.

Anti-GAP43 Antibody

M01868-3 100ul
EUR 397
Description: Rabbit Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-GAP43 Antibody

M01868-4 100ul
EUR 397
Description: Chicken Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-ATF6 Antibody

PA1011 100ug/vial
EUR 334

Anti-ATF6 Antibody

PA1011-1 100ug/vial
EUR 294

Anti-ATP5J Antibody

PA1012 100ug/vial
EUR 294

Anti-Bax Antibody

PA1013 100ug/vial
EUR 294

Anti-Bax Antibody

PA1013-1 100ug/vial
EUR 294

Anti-BDNF Antibody

PA1014 100ug/vial
EUR 294

Anti-CCR5 Antibody

PA1016 100ug/vial
EUR 294

Anti-CCR5 Antibody

PA1016-1 100ug/vial
EUR 294

Anti-CCR5 Antibody

PA1016-2 100ug/vial
EUR 294

Anti-CCR7 Antibody

PA1017 100ug/vial
EUR 294

Anti-CD22 Antibody

PA1018 100ug/vial
EUR 334

Anti-CD22 Antibody

PA1018-1 100ug/vial
EUR 334

Anti-CD40 Antibody

PA1019 100ug/vial
EUR 294

SARS-CoV-2-serologie verhoogt diagnostische nauwkeurigheid bij CT-vermoede, PCR-negatieve COVID-19-patiënten tijdens pandemie

 

Contexte :  En l’absence de détection par PCR de l’ ARN du SRAS-CoV-2 , un diagnostic précis de COVID-19 est difficile. La tomodensitométrie (TDM) à faible dose détecte les infiltrats pulmonaires avec une sensibilité élevée, mais les résultats peuvent être non spécifiques. Cette étude évalue la valeur diagnostique de la sérologie SARS-CoV-2 pour les sufferers présentant des caractéristiques CT distinctes mais une PCR négative.

Méthodes : Un  immunodosage chimioluminescent IgM/IgG a été réalisé chez 107 sufferers atteints de COVID-19 confirmé (groupe A : PCR+ ; CT ±) et 46 sufferers suspectés (groupe B : PCR- répétitives ; CT+) de COVID-19, admis dans un hôpital universitaire allemand. lors de la première obscure de la pandémie. Une classification CT standardisée et interne des signes radiologiques d’une pneumonie virale a été utilisée pour évaluer la probabilité de COVID-19 .

Résultats : Les  taux de séroconversion (SR) déterminés aux jours 5, 10, 15, 20 et 25 après l’apparition des symptômes (SO) étaient de 8 %, 25 %, 65 %, 76 % et 91 % pour le groupe A et 0 %, 10 % , 19 %, 37 % et 46 % pour le groupe B, respectivement ; (p < 0,01). Par rapport aux sufferers hospitalisés avec une évolution non compliquée (sufferers non-USI), la séroconversion avait tendance à se produire à une fréquence plus faible et retardée chez les sufferers dans les unités de soins intensifs. Le SR des sufferers avec des résultats CT classés comme haute certitude pour COVID-19 était de 8 %, 22 %, 68 %, 79 % et 93 % dans le groupe A, contre 0 %, 15 %, 28 %, 50 % et 50 % dans groupe B (p < 0,01). La sérologie SARS-CoV-2 a établi un diagnostic définitif chez 12/46 sufferers du groupe B. Chez 88 % (8/9) des sufferers avec une sérologie négative > 14 jours après l’ apparition des symptômes (groupe B), la réévaluation de consensus clinico-radiologique a révélé des diagnostics probables autres que COVID-19 . La sensibilité de la sérologie SARS-CoV-2 était supérieure à la PCR > 17 jours après l’apparition des symptômes.

Conclusions :  Environ un tiers des sufferers présentant des résultats distincts de la tomodensitométrie COVID-19 sont testés négatifs pour l’ARN du SRAS-CoV-2 par PCR, ce qui rend difficile un diagnostic right. La mise en œuvre des checks sérologiques SARS-CoV-2 aux côtés des algorithmes de diagnostic actuels basés sur la CT/PCR améliore la discrimination entre les infiltrats pulmonaires liés au COVID-19 et non liés chez les sufferers négatifs à la PCR. Cependant, la sensibilité de la sérologie SARS-CoV-2 dépend fortement du second du check et devient supérieure à la PCR après la 2 e  semaine suivant l’apparition des symptômes.

 

anti-GPCR GPR110

YF-PA22867 50 ul
EUR 363
Description: Mouse polyclonal to GPCR GPR110

anti-GPCR GPR110

YF-PA22868 50 ug
EUR 363
Description: Mouse polyclonal to GPCR GPR110

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

GPR110 Antibody

1-CSB-PA002753
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GPR110. Recognizes GPR110 from Human. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/40000

GPR110 Antibody

44961-100ul 100ul
EUR 252

GPR110 Antibody

44961-50ul 50ul
EUR 187

GPR110 Antibody

DF4891 200ul
EUR 304
Description: GPR110 Antibody detects endogenous levels of total GPR110.

GPR110 Antibody

DF2796 200ul
EUR 304
Description: GPR110 antibody detects endogenous levels of total GPR110.

GPR110 Antibody

ABD2796 100 ug
EUR 438

GPR110 Antibody

ABD4891 100 ug
EUR 438

GPR110 antibody

70R-31396 100 ug
EUR 327
Description: Rabbit polyclonal GPR110 antibody

GPR110 antibody

70R-51217 100 ul
EUR 244
Description: Purified Polyclonal GPR110 antibody

GPR110 Polyclonal Antibody

ES2448-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against GPR110 from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

GPR110 Polyclonal Antibody

ES2448-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against GPR110 from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

Polyclonal GPR110 Antibody

APR12205G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GPR110 . This antibody is tested and proven to work in the following applications:

GPR110 Polyclonal Antibody

ABP51449-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of GPR110 from Human. This GPR110 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human GPR110 at AA range: 810-890

GPR110 Polyclonal Antibody

ABP51449-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of GPR110 from Human. This GPR110 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human GPR110 at AA range: 810-890

GPR110 Polyclonal Antibody

ABP51449-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of GPR110 from Human. This GPR110 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human GPR110 at AA range: 810-890

GPR110 Conjugated Antibody

C44961 100ul
EUR 397

GPR110 siRNA

20-abx918404
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

GPR110 siRNA

20-abx918405
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

GPR110 Blocking Peptide

20-abx064092
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

GPR110 Blocking Peptide

DF4891-BP 1mg
EUR 195

GPR110 Blocking Peptide

DF2796-BP 1mg
EUR 195

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Human GPR110 shRNA Plasmid

20-abx966836
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Mouse GPR110 shRNA Plasmid

20-abx978802
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Gpr110 ORF Vector (Mouse) (pORF)

ORF046467 1.0 ug DNA
EUR 506

GPR110 ORF Vector (Human) (pORF)

ORF020338 1.0 ug DNA
EUR 405

G Protein-Coupled Receptor 110 (GPR110) Antibody

20-abx147426
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

G Protein-Coupled Receptor 110 (GPR110) Antibody

20-abx007923
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

G Protein-Coupled Receptor 110 (GPR110) Antibody

20-abx015251
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

GPR110 sgRNA CRISPR Lentivector set (Human)

K0894901 3 x 1.0 ug
EUR 339

Gpr110 sgRNA CRISPR Lentivector set (Mouse)

K3842201 3 x 1.0 ug
EUR 339

GPR110 sgRNA CRISPR Lentivector (Human) (Target 1)

K0894902 1.0 ug DNA
EUR 154

GPR110 sgRNA CRISPR Lentivector (Human) (Target 2)

K0894903 1.0 ug DNA
EUR 154

GPR110 sgRNA CRISPR Lentivector (Human) (Target 3)

K0894904 1.0 ug DNA
EUR 154

GPR110 3'UTR GFP Stable Cell Line

TU059201 1.0 ml
EUR 1521

Gpr110 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3842202 1.0 ug DNA
EUR 154

Gpr110 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3842203 1.0 ug DNA
EUR 154

Gpr110 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3842204 1.0 ug DNA
EUR 154

GPR110 Protein Vector (Human) (pPB-C-His)

PV081349 500 ng
EUR 552

GPR110 Protein Vector (Human) (pPB-N-His)

PV081350 500 ng
EUR 552

GPR110 Protein Vector (Human) (pPM-C-HA)

PV081351 500 ng
EUR 552

GPR110 Protein Vector (Human) (pPM-C-His)

PV081352 500 ng
EUR 552

GPR110 Protein Vector (Mouse) (pPB-C-His)

PV185866 500 ng
EUR 1065

GPR110 Protein Vector (Mouse) (pPB-N-His)

PV185867 500 ng
EUR 1065

GPR110 Protein Vector (Mouse) (pPM-C-HA)

PV185868 500 ng
EUR 1065

GPR110 Protein Vector (Mouse) (pPM-C-His)

PV185869 500 ng
EUR 1065

GPR110 3'UTR Luciferase Stable Cell Line

TU009201 1.0 ml
EUR 1521

Gpr110 3'UTR GFP Stable Cell Line

TU158961 1.0 ml Ask for price

Gpr110 3'UTR Luciferase Stable Cell Line

TU108961 1.0 ml Ask for price

Mouse G- protein coupled receptor 110, Gpr110 ELISA KIT

ELI-09748m 96 Tests
EUR 865

Human Probable G- protein coupled receptor 110, GPR110 ELISA KIT

ELI-08749h 96 Tests
EUR 824

GPR110 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0894905 3 x 1.0 ug
EUR 376

Gpr110 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3842205 3 x 1.0 ug
EUR 376

GPR110 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0894906 1.0 ug DNA
EUR 167

GPR110 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0894907 1.0 ug DNA
EUR 167

GPR110 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0894908 1.0 ug DNA
EUR 167

Gpr110 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3842206 1.0 ug DNA
EUR 167

Gpr110 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3842207 1.0 ug DNA
EUR 167

Gpr110 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3842208 1.0 ug DNA
EUR 167

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 277

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 277

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 277

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 277

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 277

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 277

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 277

Anti-Anti-DDB1 Antibody

A00333 100uL
EUR 455
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu
  • EUR 5698.00
  • EUR 3011.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 1 plate of 96 wells
EUR 432
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-FGF1 Antibody

RP1005 100ug/vial
EUR 334

Anti-FGF2 Antibody

RP1006 100ug/vial
EUR 334

Anti-IL3 Antibody

RP1008 100ug/vial
EUR 334

Anti-IL4 Antibody

RP1009 100ug/vial
EUR 334

Anti-DDT Antibody

RP1011 100ug/vial
EUR 334

Anti-IL6 Antibody

RP1012 100ug/vial
EUR 294

Anti-IL7 Antibody

RP1013 100ug/vial
EUR 294

Anti-IL10 Antibody

RP1014 100ug/vial
EUR 334

Anti-IL10 Antibody

RP1015 100ug/vial
EUR 294

Anti-IL10 Antibody

RP1016 100ug/vial
EUR 334

Anti-IL18 Antibody

RP1017 100ug/vial
EUR 334

Anti-CEACAM5 Antibody

RP1018 100ug/vial
EUR 334

Anti-MIF Antibody

RP1020 100ug/vial
EUR 294

Anti-NGF Antibody

RP1025 100ug/vial
EUR 294

Anti-FOXP3 Antibody

RP1032 100ug/vial
EUR 334

Anti-MUC2 Antibody

RP1038 100ug/vial
EUR 334

Anti-ATM Antibody

RP1040 100ug/vial
EUR 294

Anti-CBS Antibody

RP1041 100ug/vial
EUR 334

Anti-IL3 Antibody

RP1046 100ug/vial
EUR 294

Anti-IL13 Antibody

RP1047 100ug/vial
EUR 294

Anti-IL13 Antibody

RP1048 100ug/vial
EUR 294

Anti-MBD2 Antibody

RP1049 100ug/vial
EUR 294

Anti-FRZB Antibody

RP1061 100ug/vial
EUR 294

Anti-HGF Antibody

RP1062 100ug/vial
EUR 294

Anti-PLD1 Antibody

RP1063 100ug/vial
EUR 294

Anti-MAFA Antibody

RP1066 100ug/vial
EUR 294

Anti-SFRP4 Antibody

RP1067 100ug/vial
EUR 294

Anti-AGFG1 Antibody

RP1071 100ug/vial
EUR 294

Anti-SP1 Antibody

RP1072 100ug/vial
EUR 294

Anti-TLR8 Antibody

RP1073 100ug/vial
EUR 294

Anti-CD59 Antibody

RP1076 100ug/vial
EUR 334

Anti-TSG101 Antibody

RP1078 100ug/vial
EUR 294

Anti-CYP7A1 Antibody

RP1079 100ug/vial
EUR 294

Anti-DMRT1 Antibody

RP1083 100ug/vial
EUR 334

Anti-FABP4 Antibody

RP1085 100ug/vial
EUR 334

Anti-PTOV1 Antibody

RP1087 100ug/vial
EUR 294

Anti-Wnt7a Antibody

RP1088 100ug/vial
EUR 334

Anti-MMP12 Antibody

RP1089 100ug/vial
EUR 294

Anti-HSD11B2 Antibody

RP1094 100ug/vial
EUR 294

Anti-CD33 Antibody

RP1105 100ug/vial
EUR 334

Anti-VIP Antibody

RP1108 100ug/vial
EUR 334

Anti-SHANK3 Antibody

RP1109 100ug/vial
EUR 294

Anti-ADH5 Antibody

RP1111 100ug/vial
EUR 334

Anti-Calbindin Antibody

M03047-2 100ul
EUR 397
Description: Chicken Polyclonal Calbindin Antibody. Validated in IF, IHC, WB and tested in Bovine, Human, Mouse, Rat.

Anti-Fibrillarin Antibody

M03178-4 100ul
EUR 397
Description: Rabbit Polyclonal Fibrillarin Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat.

Anti-Fibrillarin Antibody

M03178-5 100ul
EUR 397
Description: Chicken Polyclonal Fibrillarin Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-Parvalbumin Antibody

M04041-2 100ul
EUR 397
Description: Chicken Polyclonal Parvalbumin Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Calretinin Antibody

M04255-3 100ul
EUR 397
Description: Rabbit Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Calretinin Antibody

M04255-4 100ul
EUR 397
Description: Chicken Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat.

Anti-Laminin Antibody

M04965 100ul
EUR 397
Description: Rabbit Polyclonal Laminin Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-Secretagogin Antibody

M10629-1 100ul
EUR 397
Description: Rabbit Polyclonal Secretagogin Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Secretagogin Antibody

M10629-2 100ul
EUR 397
Description: Chicken Polyclonal Secretagogin Antibody. Validated in IF, IHC, WB and tested in Bovine, Human, Mouse, Rat.

Anti-MeCP2 Antibody

M00047-1 100ul
EUR 397
Description: Rabbit Polyclonal MeCP2 Antibody. Validated in IHC, WB and tested in Human, Monkey, Mouse, Rat.

Anti-GAPDH Antibody

M00227-4 100ul
EUR 397
Description: Rabbit Polyclonal GAPDH Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-Vimentin Antibody

M00235-4 100ul
EUR 397
Description: Rabbit Polyclonal Vimentin Antibody. Validated in IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat.

Anti-Vimentin Antibody

M00235-5 100ul
EUR 397
Description: Chicken Polyclonal Vimentin Antibody. Validated in IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-CNP Antibody

M01017-2 100ul
EUR 397
Description: Rabbit Polyclonal CNP Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-CNP Antibody

M01017-3 100ul
EUR 397
Description: Chicken Polyclonal CNP Antibody. Validated in IHC, WB and tested in Equine, Pig.

Anti-GAP43 Antibody

M01868-3 100ul
EUR 397
Description: Rabbit Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-GAP43 Antibody

M01868-4 100ul
EUR 397
Description: Chicken Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat.

Anti-ATF6 Antibody

PA1011 100ug/vial
EUR 334

Anti-ATF6 Antibody

PA1011-1 100ug/vial
EUR 294

Anti-ATP5J Antibody

PA1012 100ug/vial
EUR 294

Anti-Bax Antibody

PA1013 100ug/vial
EUR 294

Anti-Bax Antibody

PA1013-1 100ug/vial
EUR 294

Anti-BDNF Antibody

PA1014 100ug/vial
EUR 294

Anti-CCR5 Antibody

PA1016 100ug/vial
EUR 294

Anti-CCR5 Antibody

PA1016-1 100ug/vial
EUR 294

Anti-CCR5 Antibody

PA1016-2 100ug/vial
EUR 294

Anti-CCR7 Antibody

PA1017 100ug/vial
EUR 294

Anti-CD22 Antibody

PA1018 100ug/vial
EUR 334

Anti-CD22 Antibody

PA1018-1 100ug/vial
EUR 334

Anti-CD40 Antibody

PA1019 100ug/vial
EUR 294

Anti-CD40 Antibody

PA1019-1 100ug/vial
EUR 294

Anti-CD44 Antibody

PA1021 100ug/vial
EUR 334

Anti-CD44 Antibody

PA1021-1 100ug/vial
EUR 334

Anti-CD44 Antibody

PA1021-2 100ug/vial
EUR 334

Anti-GJB2 Antibody

PA1025 100ug/vial
EUR 294

Anti-CXCR2 Antibody

PA1029 100ug/vial
EUR 294

Anti-dUTPase Antibody

PA1030 100ug/vial
EUR 334

Anti-DUT Antibody

PA1030-1 100ug/vial
EUR 334

Anti-FGF2 Antibody

PA1032 100ug/vial
EUR 334

Anti-FGF4 Antibody

PA1033 100ug/vial
EUR 294

Anti-GAP43 Antibody

PA1037 100ug/vial
EUR 334

Anti-Glast Antibody

PA1038 100ug/vial
EUR 294

Anti-GLUT4 Antibody

PA1039 100ug/vial
EUR 334

Anti-HMGB4 Antibody

PA1042 100ug/vial
EUR 294

Anti-INSL3 Antibody

PA1044 100ug/vial
EUR 334

Anti-KCA3.1 Antibody

PA1047 100ug/vial
EUR 334

Anti-KCNN4 Antibody

PA1047-1 100ug/vial
EUR 294

Anti-MIF Antibody

PA1052 100ug/vial
EUR 334

Anti-NGF Antibody

PA1056 100ug/vial
EUR 294

Anti-BNIP3 Antibody

PA1057 100ug/vial
EUR 294

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